These peptides were used as the sole disease-triggering agents, with the exception of the ferrous amyloid buthionine (FAB) rat [ 35], a rat model in which the AD phenotype is induced by the infusion of a solution containing the amyloid peptide Aβ1-42, the inhibitor of glutathione synthesis buthionine sulfoximine, and ferrous sulfate over 4 weeks.
Although the eitopathogenesis of migraine remains incompletely understood, it is now increasingly recognized that migraine is more complex than a sole vascular disease as previously thought [ 4- 6].
No patient had sole lateral compartment disease.
Bold type indicates evaluations in which a new nodule was the sole criterion for disease progression.
For these reasons, one should not rely on ADC values as the sole basis for disease characterization.
Thus, even in EOAD caused by mutations in APP or presenilin, Aβ may not be the sole basis of disease.
25– 27 Furthermore, many patients who develop biochemical failure (rising PSA as sole evidence of disease recurrence) after definitive local therapy are treated for long durations with ADT.
A 33-year-old woman was diagnosed in February 2004 with IPSS Low-risk MDS (no blasts, one cytopenia) and del(5)(q13q33) as the sole karyotypic abnormality, disease characteristics that are consistent with 5q- syndrome.
As sole injury and axial disease are diseases that occur principally in cows at pasture, this is the first full analysis of risk factors for those diseases.
Positive paraaortic node was the sole determinant for disease-free survival (DFS) and overall survival (OS; P<0.001).
Because each known diarrheal pathogen fulfills Koch's postulates and is capable of being the sole etiologic agent causing disease, multiple pathogens are not essential for causing disease.
