Your English writing platform
Discover LudwigSuggestions(1)
Exact(4)
Even if the sole detection of splicing events does not give information on the biological consequences of ERβ effects on RNA splicing, it is tempting to speculate on the possible implications of ERβ-dependent splicing events on BC cells.
If Mof would be closer to the DNA than Msl1, or Nsl1, respectively, in MSL or NSL complexes at certain loci, the sole detection of Mof could be explained by the suggestion of Straub et al (2013).
Although use of cycle thresholds as a semiquantitative marker has some limitations, thresholds suggest that WUPyV and KIPyV actively replicate in the respiratory tract and may account for the higher rate of reported symptoms with sole detection of WUPyV.
In some cases and since HAdV types 40 and 41 are the ones etiologically associated to gastroenteritis as well as to a high prevalence in environmental samples, assays based on the sole detection of this two types have also been developed (Table 2).
Similar(56)
During symptomatic episodes, numerous overlapping respiratory virus detections were commonly observed, which made sole detection episodes of PyV too rare to be considered in a formal statistical analysis.
MWPyV was first detected in fecal specimens from healthy children, but we found that MWPyV was the most prevalent PyV detected in respiratory specimens and that it was associated with upper respiratory infection symptoms in >33% of sole detection episodes.
Although the complex nature of virus acquisition and overlapping intervals of virus detection confound the association of PyV sole detection episodes with particular symptoms, our data show that WUPyV, KIPyV, and MWPyV, but not MCPyV, are frequently detected within the respiratory tract of healthy children <18 months of age and are associated with mild upper respiratory symptoms.
However, we observed a lower rate of PyV co-detection, which enables us to examine the association of PyV sole detection episodes with symptoms.
During the period of the sole detection episode, clinical symptoms were broadly categorized as upper respiratory, lower respiratory, nonspecific, and gastrointestinal (Technical Appendix).
We found that 1/36 participants had gastrointestinal symptoms during an episode of MWPyV sole detection, which is an observation that warrants further investigation.
However, sole detection episodes corresponded to parental reporting of clinical symptoms for 57% (4/7) of WUPyV and 36% of KIPyV (5/14) and MWPyV (13/36) infection episodes (Table 2).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com