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This is often very difficult to solve in practice particularly by applying a sole approach.
Our long-term experience with the endonasal endoscopic approach for the treatment of mucoceles led us to subsequently expand our indications to include most mucoceles, either as the sole approach or associated with an external approach.
Practically, the sole approach that may provide evidence of Mucorales presence is through histopathology using hematoxylin-eosin, Grocott-methanamine-silver and periodic acid-Schiff stains.
PCR amplification of targeted genes is employed as the sole approach to acquiring sufficient barcode sequences that are used for species identification.
This strategy as a sole approach should be discouraged, as it cannot provide the necessary insulin requirement in patients recovering from hyperglycemic crisis and β-cell failure.
When all attempts through HIER fail, one could opt for protease induced epitope retrieval (PIER), although some scientists prefer PIER over HIER as their sole approach.
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Until recently, the combination of early detection, case management, and reactive immunization using polysaccharide vaccines were the sole approaches available to control these epidemics.
Assessing the different approaches for controversial microsurgical management of complex aneurysms (aneurysms without a sole optimal approach) can provide scientific solutions to surgical dilemma.
Two striking facts surround the practice of vaccination: It is the sole medical approach to have fully annihilated a disease, yet the development of most effective vaccines took place without considering the intricate cellular processes they wish to effectuate.
Background During the last two decades of the 20th century, hormone replacement therapy (HRT) has been considered as the sole pharmacological approach for counterbalancing or mitigating the effects of estrogens deprivation in post-menopausal women.
Especially patients with multiple known risk factors for early recurrence do certainly not benefit from a sole surgical approach.
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