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We calculated the daily SOFA score of the patients with an initial SOFA score higher than 9. IGSII, LOS and mortality were compared between patients with a SOFA score higher than 9 for at least 5 days (SOFA group) and the other selected patients (SOFA group).
Concerning sepsis severity, SOFA score was higher in the higher SOFA group (p = 0.04) (data not shown).
Platelet inhibition with cytochalasin revealed stronger impairment of MCF in the high SOFA group.
Patients in the low Sequential Organ Failure Assessment (SOFA) group were administered a mean of 1,373 ± 1,929 ml over the whole study period; those in the high SOFA group received 2,523 ± 1,914 ml.
The mortality rate of the SOFA group increased but remained far from values permitting to withdraw or withhold intensive care.
In patients with higher scores for organ failure, MCF differed from the low SOFA group during the first 48 hours.
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Differences of median PCT levels between these SOFA groups were analyzed by the Mann-Whitney U test.
After verification of skewness, septic and nonseptic patients and SOFA groups were compared using the Mann–Whitney U test.
The director M. Night Shyamalan ("Signs") was mingling in a corner, and, on one sofa, a group was politely debating Courtney Love's authenticity as a musician.
Finally, higher SOFA score group (p = 0.01), but not lower SOFA patients (p = 0.24), increased CD34+/CD45−/VEGFR2 + EPCs number.
13613_2017_268_MOESM1_ESM.doc Additional file 1. Mean survival time (days) in the SOFA <8 group based on immunoglobulin thresholds.
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