The social deficits of the oxytocin knockout mouse.
A new mouse model could shed light on the social deficits that characterize this complex disease.
Autism is characterized by social deficits, communication abnormalities, and repetitive behaviors.
Our findings deepen our understanding of the mechanisms at play in the social deficits of individuals with autism.
Social skills training is a frequently utilized intervention for addressing social deficits of children with autism spectrum disorder (ASD).
They study language and social deficits — the hallmarks of autism spectrum disorder — as well as challenging behaviors common to autistic children, like hand flapping, tantrums or self-injury.
Takayanagi Y, Yoshida M, Bielsky IF, Ross HE, Kawamata M, Onaka T et al. Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice.
Karl Deisseroth and colleagues at Stanford University used light to trigger and then alleviate social deficits in mice that resemble those seen in autism.
Although standard behavioral interventions for autism spectrum disorder (ASD) are effective therapies for social deficits, they face criticism for being time-intensive and overdependent on specialists.
Although small-scale studies have described the effects of oxytocin on social deficits in autism spectrum disorder (ASD), no large-scale study has been conducted.
These disorders are typically characterized by social deficits, communication difficulties, stereotyped or repetitive behaviours and interests, and in some cases, cognitive delays.
