The natural history of prostate cancer prevents the use of mortality as an outcome measure in most short- to medium-term reports of prostate cancer therapy, so surrogates in the form of biochemical failure have emerged.
And he no longer has the pillar of the Queen family to lean on, because obviously Robert Queen's gone, so his surrogate father's gone; now his surrogate brother is essentially gone, and absent, at least in the capacity that he once was.
So, the surrogate mother cannot be forced into giving up the child if she bonds with it and changes her mind.
For this reason, clinicians and health authorities have relied on so called surrogate end points to assess the efficacy of any therapeutic intervention for viral hepatitis.
The design of experimental facility and instrumentation becomes complicated with use of liquid sodium, so a surrogate fluid can simplify the design and operation considerably, providing flexibility to obtain high quality measurements.
For general design basis accidents, such as SBLOCA and LBLOCA, the traditional deterministic safety analysis methodologies are always applied to analyze events based on a so called surrogate or licensing sequence, without considering how low this sequence occurrence probability is.
However, fishing vessels do not necessarily go to the nearest port to offload their fish, so our surrogate could be improved by including more detail on the cost-benefit relationship between the profitability of different ports and different fisheries.
However, having access to such target tissue is not usually possible and so a surrogate target tissue was sought for the in vivo studies.
Russia's president Vladimir Putin has ordered the government to crack down on so-called surrogate alcohol, as the death toll from consumption of a fake batch of bath tincture exceeded 60.
Perhaps the most controversial form of assisted reproduction is so-called "surrogate" motherhood.
