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All of these indicate that in majority of cases pain is so severe that is intolerable.
The infection was so severe that she required intravenous antibiotics and several nights in the hospital.
Sometimes, disasters are so severe that tenants can never return.
The jet lag is so severe that sleeping is impossible.
New Jersey's financial problems are so severe that even Gov.
Eventually my depression was so severe that I became suicidal.
The diarrhea from cholera is so severe that patients can die within hours from dehydration.
The damage was so severe that neither side has been able to prove what happened.
Lara's injuries were so severe that he was kept in a medically induced coma for weeks.
The conflict had become so severe that they had been forced to leave their homes.
The collision was so severe that a tooth fragment was stuck in his arm.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com