When the NP moves near the wall, it is attracted by the receptors, so it progresses to the wall and is bound to it, at which point the curve reaches the maximum MSD.
Even if amyloid does trigger the disease process, by the time symptoms become obvious "the disease becomes independent of amyloid, so it progresses even if the amyloid is removed," says Scott Turner of Georgetown University.
"Some chapters are five times as long," he observes, "and the book gets more complicated as it progresses, so it could take another 30 years".
Once the blowout started, it progressed so rapidly that the Horizon itself was doomed.
But I should have actually probably got it seen to a lot earlier than I did.' (P3, male, change in the appearance of a mole) 'But then it progressed so that I was coughing during the day and then it even progressed more that it was actually waking me up during the night.
Symptoms in this category were becoming more visible over time and this, in combination with sanctioning from peers, triggered help seeking: 'But then it progressed so that I was coughing during the day and then it even progressed more that it was actually waking me up during the night.
But they're at a point now where it is stabilising and so it is progress".
But the whole point of screening is to look for trouble early so it does not progress over time.
Oakley added: "He's training here and has been working very hard while the boys have been away in South Africa, so we'll see how it progresses as time rolls by.
"We have been in this situation before - in 2010 when we drew with Fiji, and Samoa last year, when we lost - so it shows we have progressed.
