Sentence examples for snare that is from inspiring English sources

Inhibition of a target SNARE that is involved in secretory transport leads to selective inhibition of caveolar endocytosis.

They determined atomic-resolution structures by single particle electron cryo-microscopy which show a protein called NSF alone and interacting with its target, a protein complex called SNARE that is formed when membranes fuse together.

Precedence for this comes from work describing TNO1, a SNARE that is important in vacuolar trafficking and that is required for co-localization of SYP61 and VHAa1 (subunit a1 of the vacuolar ATPase) at the TGN (Kim and Basham, 2011).

Likewise, a major shift of the localization of synaptobrevin 2/VAMP2 (Syb2), a vesicular SNARE that is internalized by clathrin-mediated endocytosis, was observed in TKO MEFs stably expressing Syb2-HA, (this construct harbors the HA epitope at the very short C-terminal non-cytosolic portion of Syb2).

- The SNARE proteins are broadly classified into two main categories: the v-SNAREs that are primarily found on the transport vesicle and the t-SNAREs that associate with the target membrane., Besides being structurally distinct, the v-and t-SNAREs perform different functions.

Each vacuole has four SNAREs that are required for homotypic fusion: the R-SNARE Nyv1p, the Qa-SNARE Vam3p, the Qb-SNARE Vti1p, and the Qc-SNARE Vam7p (Nichols et al., 1997; Ungermann et al., 1999).

HeLa cells expressing KChIP1 EYFP were stained with antibodies recognizing SNAREs that are present in only one of the three complexes implicated in ER to Golgi traffic.

Coiled-coil tethering factor p115 interacts with specific COPII associated SNAREs that are required for homotypic tethering of COPII vesicles, and subsequent VTC formation (Allan et al. 2000).

VAMP2 is a SNARE protein that is located on the insulin-containing vesicles that are responsible for insulin secretion in endocrine pancreatic beta cells (Regazzi et al., 1995).

In this work we describe the function of VTI13, a SNARE protein that is important for root hair growth.

Voltage-gated Ca2+ currents were assessed with Ca2+ imaging and whole cell recording, while immunocytochemistry was used to detect expression of SNAP-25, a presynaptic SNARE protein that is associated with conventional synapses in taste cells.