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The uptake of praziquantel in the snack schools was 94%% compared to 79%% in the non-snack schools.
The uptake of praziquantel in the snack schools (93.9 %) was considerably higher than in the non-snack schools (78.7 %).
Of the 1,284 children assessed in 2013, 595 (46.3 %) were from the snack schools and 689 (53.7 %) were from the non-snack schools.
The proportion of children who reported to have eaten something prior to mass treatment in 2014 was 54.4 % (95 % CI 48.8 58.9%%) in the snack schools compared to 32.5%% (95 % CI 28.2 37.0%%) (p = 0.011) in the non-snack schools.
Because of the cluster design, a design effect of 6.3 from the previous study was applied to obtain a minimum sample size of 536 in the snack schools and 536 in the non-snack schools.
The occurrence of the side effects as well as the prevalence and geometric mean intensity of S. mansoni infection were considerably lower in the snack schools than in the non-snack schools [ 27].
At a 90%% power and a 95%% CI, the sample size required to test this difference was 85 in the snack schools and 85 in the non-snack schools according to STATA 12.0 (TX, USA).
The occurence of side-effects attributable to praziquantel increased from 34.4 to 61.2%% (p = 0.001) in the snack schools but was unchanged in the non-snack schools; 46.9 and 53.2 % (p = 0.443).
Uptake of praziquantel reduced from 93.9 to 78.0%% (p = 0.002) in the snack schools but was unchanged in the non-schools 78.7 and 70.4 % (p = 0.176).
Each child in the snack schools received 500 ml of mango juice and a doughnut shortly before swallowing praziquantel during mass treatment.
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