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To uncover the entire CCCH family in mouse and human, we first searched several database including EMBL-EBI, Pfam and SMART using the terms "CCCH-type zinc finger" or "C3H-type zinc finger".
Through prediction by SMART using the full sequence of identified bHLH members whose protein accession number were available (Additional file 3), we found that: a) Among members of group C, there are 4 sequences having one bHLH, one PAC (Motif C-terminal to PAS motifs) [ 26] and two PAS (PER-ARNT-SIM homology) domains, while EFN88377.1 has one bHLH, and two PAS domains.
Functional assignment of the predicted genes was achieved by searching for homologs in public protein databases, such as UniRef100, Swiss-Prot, the GenBank nonredundant protein database, KEGG, and SMART, using the Basic Local Alignment Search Tool BLASTT) program (Altschul et al. 1997).
InterProScan was used to annotate motifs and domains in yak genes by comparing them to hits from the public Pfam, PRINTS, PROSITE, ProDom and SMART using the HMMPfam, FPrintScan, ScanRegExp, ProfileScan, BlastProDom and HMMsmart with the following parameters -format raw -goterms -iprlookup.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com