The SUCAST Project (Sugarcane Signal Transduction) [ 26, 27] used BLAST searches, Pfam and SMART domain analysis to identify conserved signal transduction components such as receptors, adapters, G-proteins, small GTPases, members of the two-component relay system, nucleotide cyclases, protein kinases, protein phosphatases, elements of the ubiquitination machinery and transcription factors.
For instance, motif 8, which was conserved in C6 members, was characterized as involved in apoptotic signaling and has SPT5 protein-binding characteristics according to SMART analysis.
Subsequently, we performed SMART and Pfam analysis to find the putative CCCH protein sequences [ 39, 40].
That is smart analysis by a public relations firm trying to understand the public's relationship with the institutions and companies it serves.
Finally, based on the Pfam and SMART analysis, we refined the search results manually to further reduce hits with partially conserved functional domains and other false positives.
Pfam and SMART analysis using the derived sequences were then carried out to eliminate false positives.
I like smart analysis, considered opinions, I tell myself, not two assholes trying to be more gaping than one another.
Simple Modular Architecture Research Tool (SMART) analysis indicated that ChNFIL3 has two basic leucin zipper domains, similar to the other known NFIL3 family proteins.
SMART analysis [ 22, 23] revealed the existence of seven transmembrane domains, common to all chemokine receptors.
