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The smallest number of cases was recorded in children aged 40 to 60 months - an age group which is currently well protected by two doses of MMR vaccine.
One reason for a lack of statistical significance may be a lack of power, and this type of defect had the smallest number of cases (33) and hence the lowest power to detect any association.
The smallest number of cases remaining at three years in any group was 43 in the group who had been treated with high dose rate brachytherapy.
The physicians that did not participate were, for the most part, GPs, which was the category of physicians that reported the smallest number of cases.
C4.5 allows the setting of several parameters that influence branching and quality of the final classification tree: most notably there is one parameter that determines the smallest number of cases to be included in a single group (mentioned already above in table 1), and another parameter that determines the degree of post-pruning performed.
The most recent study with the smallest number of cases (n = 37) yielded large variance in the effect estimate; removing this study led to almost the same summary RR (0.62; 95% CI 0.56 0.70; P for Q statistic = 0.35, H = 1.0 [1.0–1.3], and I = 9% [0 44]).
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Also, a small number of cases have occurred among newborns.
"We continue to see a small number of cases or suspected cases coming forward.
Sexual transmission of Zika virus has occurred in a small number of cases.
A small number of cases of sexual transmission have been reported in the US and elsewhere.
Treatments range from ice packs to bite plates or, in a small number of cases, surgery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com