Conservation of a homodimeric structure is consistent with the concept that dimerization is important for HSL function and the smallest functional unit of HSL could thus be the homodimer.
The smallest functional unit of cancellous bone is the single trabecula.
The hepatic tubule with its associated microvasculature likely represents the smallest functional unit of this important organ.
Results suggest that VCP is the smallest functional unit able to bind C3b, thereby blocking complement activity, and only a single site, the large basic region near the C-terminus, is involved in heparin binding.
Across many tissues and organs, the ability to create an organoid, the smallest functional unit of an organ, in vitro is the key both to tissue engineering and preclinical testing regimes.
The antibody Fv fragment is the smallest functional unit of an antibody but for practical use, the VH/VL interface requires stabilization, which is usually accomplished by a peptide linker that joins the two variable domains to form a single chain Fv fragment (scFv).
If a protein domain represents the smallest functional unit of evolution, and if the role of an organism within its ecological niche can be represented by the sum of its functional parts, then a comparison of a genome's 'parts lists' should group organism by ecological niche.
The motion segment is the smallest functional unit of the spine[ 1].
Third, single-cell resolution provides clinicians and researchers with the unique opportunity to directly investigate the molecular heterogeneity of CTCs on a cell per cell basis, the smallest functional unit of cancer.
Given that, the smallest functional unit that displays full regulation of kinase activity is the six-receptor-dimer, one-CheA-dimer, two-CheW unit that also seems to be the basic building block of array assembly, and all the reconstitution protocols explored here produce such functional units.
