However, despite the obvious benefits of murine models (including experimental simplicity, small size, familiarity, ease of husbandry and relative low costs), these differences mean that these animals do not faithfully model the clinical situation in DMD: therapeutic trials can be hard to assess in mildly affected mdx mice and are difficult to interpret in double-mutant mice [18].
But like others, she said she missed the languid pace and small-town familiarity.
IMPROBABLE though it may seem, New Yorkers viewed their city with a certain innocence, living with small-town familiarity in self-sufficient neighborhoods and filling their basic needs without needing to travel more than a few blocks.
Although there is still a certain level of small-town familiarity among residents, he said, it is tempered by an influx of newcomers, a freestanding Starbucks and an increase in both traffic and teardown construction — the same elements encountered in any Chicago suburb.
Because the number of consultations with a familiarity-score of 1 (not at all/hardly familiar) and 2 (moderately familiar) was smaller than category 3 (very familiar), consultations with familiarity scores 1 were chosen first, followed by consultations of the same GP scoring 2 and 3 on familiarity.
Dino had a comfortable familiarity with small-town rituals and obligations, and he rarely declined when asked to donate his time and expertise to community organizations.
A smart watch, on the other hand, would feel a lot more like using a really small smartphone, and that familiarity makes the watch a great bridge between smartphones and computational headsets.
Although the relative difference in perceived familiarity was smaller for odors than for faces, the familiarity effect on recognition was true for both modalities (Klatzky and Forrest 1984; Rabin and Cain 1984; Murphy et al. 1991; Trinkler et al. 2009).
However, each of the identified genes has a relatively small effect on disease risk, explaining only a very small part of the observed familiarity in type 2 diabetes (Saxena et al., 2007; Sladek et al., 2007; Zeggini et al., 2007; Dupuis et al., 2010; Voight et al., 2010).
But this is happening in a small town, where proximity and familiarity make a sudden reordering all the more difficult.
