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The candidates range from the smallest challenge at 149 Da to the biggest at 1256 Da with the average hovering around 419 Da. Figure 21 The distribution of structures relative to the molecular weight across 100 Double and Single Agreement challenges.
The smallest challenge -- from a new paperwork requirement to a higher health insurance premium -- can push a self-employed business from the edge to oblivion.
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When we talk about raising children and securing their future, even the smallest challenges, like paying for clean diapers, can have lifelong consequences.
It's no small challenge.
That is no small challenge.
prints of vintage films — no small challenge.
It is no small challenge.
Mr. McAdams, 25, faces no small challenge.
Rolls-Royce is a much smaller challenge.
This is no small challenge theatrically, however.
The drills were no small challenge.
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