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The smaller study groups -- hallmarks of Mr. Williams's tenure -- had been essential, he said.
A second smaller study compares stomach side effects in Arcoxia against diclofenac in about 4,000 rheumatoid arthritis patients.
An earlier, smaller study in California also found a modest increase in risk.
The test did not work for women not treated with tamoxifen, according to a separate, smaller study also presented at the conference.
This study confirmed the findings of a smaller study on the safety of farmed salmon that was released last summer by an advocacy group, the Environmental Working Group.
A smaller study of CRP, using the same method and published last October in The New England Journal of Medicine, came to the same conclusion.
Researchers got a glimpse of that complication from a smaller study conducted in Manhattan eight years ago, Mr. Kalb said.
It is broadly consistent with his smaller study of missions to Mir, the Soviet Union's first space station.
And unlike the subjects in the smaller study, the participants in the national trial were paid $2 per session and an additional $10 at the end of each week for their participation.
Dr. Magnus Lindh, a diarrhea specialist at the University of Gothenburg in Sweden, who led a smaller study in Rwanda, said many children had several gut pathogens simultaneously and it was hard to know which caused their diarrhea.
And another smaller study of V.A. medical centers in the New York area found that more cases of post-traumatic stress disorder were diagnosed among veterans than expected in the nine months after Sept. 11.
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