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Or should she decide that since, on average, women with estrogen-fed tumors gain a small survival benefit from chemotherapy, she cannot forgo the treatment?
A spontaneous shag is hard to plan for, but for a big date that is likely to end well, packing a small survival kit means you can extend to brunch.
The author Ali Smith, who cites Paley as a "definite" influence on her own short stories, believes that if she does not get the recognition she deserves outside America it is because "she is about things that do not suit a high profile: the short form, the political everyday, the small survival (which is, actually, epic), the playful potential, the unsentimental hope.
In a meta-analysis of 119 patients by Kinney from 1989, there was a small survival benefit with anticoagulation (70%) when compared to surgical embolectomy or thrombolysis (62%) [5].
After local and hormonal treatments, a great number of patients ultimately progressed to castrate-resistant prostate cancer (CRPC), in which chemotherapy provides a small survival advantage, but with significant toxicities.
The contact effect is of fundamental interest to radiobiologists and radiotherapists because small survival differences in the low-dose region of the survival curve are magnified during a conventional course of fractionated radiotherapy.
Small (survival) treatment effects, limited patient populations, and the increasing number of left ventricular assist devices in development challenge the efficient conduct of premarketing trials (especially in destination therapy) and, maybe more importantly, hamper innovation.
Is it because you only have small survival spaces in an aircraft and the smaller you are, the more likely you are to survive?" Curtis told ABC News.
Gemcitabine-based chemotherapy for locally advanced or metastatic PDAC has only modest activity with a small survival benefit [3].
The same studies mostly failed to show a difference in overall survival [30], [32] although a small survival advantage was found in a single study [31].
How can this small survival benefit be further improved?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com