The advantage of AMGP over a sire model based on two-step genomic predictions is expected to increase as the number of genotyped cows increases and for species, with smaller sire families and more dam relationships.
The latter advantage is expected to increase as the number of genotyped cows increases and also for species, with smaller sire families and stronger dam relationships, for which the use of animal models is crucial.
Alternatively, the unusual heterochiasmy pattern documented in the domestic IMF might simply be an artefact resulting from the facts that the population size was small, all sires descended from a single grand-sire and there were only three maternal grandsires compared to 13 granddams.
Seabiscuit was a bay and on the small side, unlike his sire, who more closely resembled Man o' War.
Farmers began to report late gestation abortions and the stillbirth of small calves sired by this bull one year after the initial inseminations.
The highly significant negative coefficient for FIC strongly suggests that using MY0 can 'over-adjust' for FIC, and that the relatively small estimate of sire variation for MY0 was due to the offspring of some sires being more likely to have reduced feed intake when repeatedly confined in the RC.
Most, if not all veteran producers can tell if a young bull will sire small calves simply by looking at his conformation and his EPD numbers based off the genetics and EPDs of his sire and dam).
When the total editing resources were limited, the number of distinct QTNe across the 20 generations of GS + PAGE was much greater when these resources were focussed on a small number of sires as opposed to all sires (Table 4).
The increase in inbreeding was much greater when a fixed amount of PAGE resources was focused on a small subset of sires than when the PAGE resources were spread evenly across all sires, which resulted in basically the same level of inbreeding as that obtained with GS only.
In the first generation, distributing the edits across a small number of sires (T5se) never led to better results than distributing them across all sires (A25se) [See Additional file 1: Figure S1].
