The small replicating molecule is called a DNA vector (carrier).
The feature of small replicates and large gene numbers, e.g., about 6,000 in yeast and 23,000 in Arabidopsis, in microarray data usually results in poor estimation of gene-specific variances.
This time, a newly diagnosed PBC cohort, albeit small, replicated the previous finding by Japanese GWAS [ 12] that a STAT4 SNP at rs7574865 was associated with susceptibility to PBC.
We found that WAD was the best for some datasets which contain large (> 10) replicates (e.g., Datasets 5, 7, and 26) while FC and RP tended to perform the best on datasets with relatively small replicates (e.g., Datasets 34 and 10, whose numbers of replicates in one class were smaller than 6) [see Additional file 1].
For the first datasets comprising more than 100 million sequences, the highest N50 values were obtained for k = 17, for the smaller replicate datasets for k = 18.
Assembling the smaller replicate datasets produced less contigs than assembling the larger datasets because increased sequencing depth facilitates detection of a higher number of transcripts.
For the purpose of studying mechanisms of tumor onset we focused on a subset of hybridizations comprising normal (four replicates), transgenic (three replicates), and small (one replicate from pooled samples) as well as medium-size (four replicates) tumor states.
The interruption of late replicating L1-rich AT isohores by small early replicating (EtoL) domains and early replicating L1-poor GC isohores by late replicating (LtoE) domains was also thought to be a feature associated with pluripotency [ 45].
When the painting is done, she puts on the finishing touches, including tiny red veins, which are too small to replicate with a paintbrush, even the size 0 and 00 red sable brushes that ocularists favor.
