He earned one of the night's warmest responses by proposing that drug tests be mandatory for anyone receiving federal assistance — in essence, a small-government rationale for state surveillance.
This is exactly the rationale for small modular reactors – proponents argue that in building much larger numbers of smaller reactors they can benefit from learning-by-doing and decrease costs.
The recent development of ACP xenotransplants in immune deficient mice [ 24] will enable pre-clinical testing of these rationally selected targeted therapies, providing further rationale for small studies on efficacy in augmenting surgery and radiation or in treating recurrent ACP.
Yes, I've heard the argument that those who earn over $250,000 are a small group - as if small numbers is a legitimate rationale for profiling.
Since complication rates are dependent on the irradiated volume, the rationale for smaller safety margins is an optimization of the risk-benefit ratio [ 33, 51]; initial clinical data on IMRT for soft tissue sarcomas of the extremity have shown local control of 96%% at 3 years with small margins of 2 cm [ 52].
This provides a rationale for developing small-scale arrays, enabling cost-effective studies of a limited number of genes involved in specific biochemical pathways [ 6- 9], thus allowing more detailed studies of specific biological processes.
Offering his rationale for thinking small, Mayor Whelan put it his way: "The problem with something big is that you have to get everyone to agree and consensus seems impossible.
Furthermore, our calculations offer a rationale for the small effect on binding affinity observed upon specific mutations involving large changes in electrostatics (i.e., the charged-to-neutral mutations).
The effects of NSC23766 provide a rationale for targeting small GTPases in ALK-dependent cancers.
Collectively, these studies suggest that targeting Skp2 may be an ideal therapeutic strategy for human cancer, therefore establishing a rationale for designing small molecule inhibitors of Skp2 for the treatment of human cancers.
The rationale for transplanting small parts of minced tissue for epithelial cells expansion by using the patients own body as a bioreactor has been discussed in previous publications [ 12, 13, 16].
