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These techniques often downplay the importance of interaction variables that have small predictive ability but that are critical when the ultimate goal is decision making rather than prediction.
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Our study was unable to identify the other risk factors found in THIN and QResearch [ 17] that add small additional predictive abilities, as we were only powered to find strong risk factors.
When compared with REMS, RTS substitutes a small amount of predictive ability in return for simplicity.
Our objective to properly incorporate genotypes into a kernel had a small impact on predictive ability of yet-to-be observed phenotypes.
Nevertheless, there remains a small difference between the predictive ability of ICD-9 and ICD-10 models.
However, in these studies, the correlations between hand BMD and joint damage were found to be small suggesting that the predictive ability of HBL for joint damage may be limited.
Predictive ability of each model was assessed by the sum of χ values and the proportion of wrong predictions for mastitis incidence, where smaller values indicate better predictive ability.
Performance of this model was better in terms of both predictive ability (smallest AIC) and discrimination power (AUC close to 0.70).
We also considered a fivefold cross validation splits a set of 20 compounds into 5 subsets of 4 compounds each, so it is unsurprising that the models do not maintain their predictive ability for small classes.
Combining SNB status with those clinico-pathological features, however, does produce a small further increase in prognostic predictive ability.
To facilitate interpretation of results, we conducted a minor analysis investigating the predictive ability of the selected biomarkers in the smaller sample of participants who did not develop MetS on follow-up (N = 937).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com