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This analysis allows the identification of small fraction of samples showing statistically significant variations in gene expression from the rest of the population patient cohort, thus bypassing the usual problem of the intrinsic heterogeneity present in all analyses based on clinically derived tumors [23].
The current exponential rate of data submission nevertheless makes manual annotation impractical, leaving a curated annotation index for only a small fraction of samples (Supplementary Fig. S1).
This also restricts the ability to examine the E2F4 signature in certain breast cancer subtypes accounting for only a small fraction of samples.
A small fraction of samples showed many events, but the number of CNVs identified in each single cell sample was not correlated with MAPD score.
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According to the story, Theranos' novel system for blood analysis, called Edison, was only being used to analyze a small fraction of blood samples at the end of last year and some employees doubted its accuracy.
A small fraction of these samples were fixed in formalin for immunohistochemistry or prepared for miccroarray analysis as previously described[31].
Notably, a small fraction of NSCLC samples (11%) do not express IR-B.
In our study only a small fraction of blood samples were hypoglycaemic (0.25 %), but this nevertheless affected 8.9%% of patients following introduction of SGC (Table 3).
Well-designed substudies, however, can be carried out within the NCS cohort using only a small fraction of the sample size (possibly < 10% of the study sample)—to estimate and adjust for exposure measurement errors, with sufficient power to characterize the relationship between exposure and health outcome for most hypotheses.
This is especially advantageous for applications where only a small fraction of the sample should be analyzed, or more importantly, where the sample is composed of a few cells only.
Water bodies in all urban land covers were dominated by lakes and ponds, while reservoirs and wetlands comprised only a small fraction of the sample.
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