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The Bonferroni correction widely applied to human GWA analyses imposes a substantial multiple testing penalty, effectively limiting the ability to detect loci with small effects to reduce the detection of spurious loci.
Coronary artery disease (CAD) is often polygenic due to multiple mutations that contribute small effects to susceptibility.
"According to our observations, damages to crops, pastures and small effects to the health of people are already evident," the Ecuadorean geophysics institute said.
Poincaré discussed examples that, in hindsight, we can view as raising doubts about taking explosive growth of small effects to be a sufficient condition for defining chaos.
The fact that different linkage peaks are identified within and between the major global foci on VL in India, Sudan and Brazil is not necessarily surprising, since the complex nature of the disease means that we expect many loci to contribute small effects to disease susceptibility.
The other methods assign relatively small effects to most of the SNP.
Similar(42)
Therefore, little disruption like noise causes a very small effect to disturb orthogonal property encoded in U and V [33].
The quantization level has small effect to the algorithm 1 and it achieves almost same performance as full Pe case in the observing SNR range.
Each of these genes may contribute a small effect to the pathology of schizophrenia.
Larger stimuli have slightly wider profiles, but the profiles largely overlap, implying that four-fold increase in the stimulus size has a remarkably small effect to the tuning.
This example clearly demonstrates the importance of finding QTL with small effect to understand the genetic basis of spikelet number.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com