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The potential for harm associated with radiation exposure is cumulative; as survivors age and continue to be imaged, small effective doses will accumulate to even higher life-time exposures.
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Some recent dosimetric studies state that CBCT scans produce a smaller effective dose to patients if compared to multislice CT scans[26, 27].
Nevertheless, identification of critical sites of targeted delivery along with increased delivery efficiency would enable the smallest effective dose.
All psychoactive drugs should therefore be used judiciously in critically ill patients, in the smallest effective dose for the shortest time necessary.
(A) Start the treatment from a smaller effective dose, gradually increase the dose or add combined drugs; the goal is to lower the blood pressure to the standard within 1 to 2 weeks.
Take all pain medications according to the dosage on the label, and always take the smallest effective dose.[74].[74]
A few have been collected in Table 7 and they illustrate how small the effective dose (which also accounts for the gonad dose) of pelvic radiography in children is.
It may make a difference if all surgical patients (including those who actually will not need an antiemetic) receive prophylactically a high dose of an expensive drug, or if only those who are suffering from PONV symptoms will be treated with a small (but effective) dose of the same drug.
This technique has the potential of a smaller effective patient dose, which has been reported to be 1 3 mSv in adults [12] and 0.2 0.7 mSv in newborns and infants [11].
The key issue seems to be also minimizing or eliminating the side effects resulting from the use of medicines in smaller but therapeutically effective dose [ 3].
Phytoalexins are small molecules of extreme structural diversity and with effective doses around order of magnitude 10−5 10−4 M.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com