Sentence examples for slowing down expression from inspiring English sources
However, many of the commercial vectors encoding different solubility tags require different cloning and purification steps for each vector, considerably slowing down expression screening.
Our findings in MDA-MB-231PAC10 cell line, for example, high p21 expression, cell cycle slowing down and high expression of Pgp, indicate that the high population of CSCs in this cell line may play a crucial role for the pan-resistance.
When an overabundant or overactive protein leads to disease, common therapeutic approaches include small molecules that bind to the active site of the protein and interference RNA molecules that slow down the protein expression.
Unfortunately, it was not effective in slowing down the clinical expression of Alzheimer's disease.
To overcome the toxicity of expressed protein, we modified expression strategy to slow down protein expression by growing the cells at 30°C in Luria-Bertani growth medium containing 1% glucose and induction with 0.1 mM IPTG for 3 h, which resulted in highly efficient induction of protein in the cell lysate at 50 kDa [Fig. 1b, left panel, encircled].
Accordingly, down-regulation of Engase1p expression slows down the conversion of fOSGN2 into fOSGN and, similarly to down regulation of Man2c1p, reduces the rate at which small fOSGN gain access to the lysosome and extracellular space.
Consequently, ECRG4 and ECRG1 co-expression slowed down cell cycle progression and enhanced cell cycle G1 phase block in ESCC cells.
A recent study revealed that the positive feedback regulation slows down the kinetics of gene expression in a synthetic gene circuit and contributes to the response delay [34], indicating that the positive feedback regulation of Per2 slows down the accumulation of PER2 protein and may affect the phase of the circadian clock.
