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It is known that, because of the slow course of aging, the nervous system can compensate and maintain adequate function even in centenarians.
The slow course of gastrointestinal research in autism — still a controversial subject — has fewer public-health implications than dropping vaccine rates do, but it is an interesting footnote, one of the odd legacies of Wakefield's work.
We found ourself idly tracing the slow course of planes across the sky at night as we lay in bed, despite out having been told that a V-bomb sounds more like an old motorcycle than a plane.
Some relapsing patients might have died at home without a diagnosis being made, but given the slow course of the disease and the short distances to Nioki hospital, this situation probably did not occur very often.
Differences in cellular changes observed in necrosis versus apoptosis can be well documented, and the slow course of apoptosis is well suited to time-lapse recording (Collins et al. 1997).
Because of the slow course of prion infection, it might take significant time to spread the infection to brain areas vital for survival, such as brain stem and midbrain, where production of sufficient PrPres and other toxic products to induce significant dysfunction would also be required.
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Several lines of evidence have stressed in recent years the importance of HLA class I genotype in predicting progression [34], [35], [36] with certain alleles associated with a slower course of the infection.
This 'deleted'low-copypy' mouse undergoes a slower course of disease, over many months.
In this latter case, we assume that the slower course of G37R/L76WT mice is due to slightly lower expression of the WT hSOD1 transgene (Fig. 1).
Tumors that contain this codeletion have been shown to be associated with an oligodendroglial phenotype, a slower course of the disease and a better response to chemotherapy.
Further studies will employ another variant of SOD1G93A mice that carries a deletion of the transgene array to reduce the copy number and thus undergoes a slower course of disease (49).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com