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They observed that anchored specimens first exhibited complete FRP debonding followed by significant slippage compared to unanchored specimens, as well as higher joint capacity.
These results suggest that the HSY is less vulnerable to mutation caused by replication slippage compared to other chromosome regions to maintain its unique sequence feature.
The higher frequency of SSRs in the transcribed region of the genotype F6 could indicate, that the genome of this genotype is more prone to mutations and/or DNA polymerase slippage compared to the genome of the other two genotypes.
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The helical gear offers high contact and more friction which avoids slippage when compared to spur gear.
Intron I of Theileria species appears to have undergone intron slippage, when compared to the position in amoebozoan, fungal, or metazoan genes, as the intron site falls within the proposed 12 bp limit for intron displacement [ 51].
Based on the short length of homopolymeric tracts identified in C. pecorum ATs (maximum 8 nucleotides), it appears less likely that expression of these genes are subject to phase variation by strand slippage mechanisms compared to ATs from other organisms such as C. abortus (maximum 16 nucleotides).
However, Scenario 2 (non-ideal passive wheels) has a limited region where the slippage ratio is high, compared to Scenario 3, where a whole region seems to give high values of slippage ratio.
Similarly, (AT/TA) n dinucleotides form stronger hairpins and contain a smaller number of hydrogen bonds making them more vulnerable to slippage, compared with (AG/CT) n and (AC/TG) n TRs (Casasnovas et al. 1993; Sinden 1994).
Compared to the slippage pathway, the pathway that triggers cell death in mitotic arrest is less clear.
The dominance of relatively short STRs in the genome of D. pulex indicates that the 'life cycle' of a typical TR is comparatively short, i.e. the frequency of interrupting point mutations is relatively high compared to extending slippage mutations.
In general, models that allow chimps to have a larger per-repeat unit slippage rate and/or a shorter focal length compared to humans give a better fit to the human-chimp data as well as the human genomic data.
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