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For the sake of clarity only those results obtained with the whole protein and the SLiM region with and without flanking residues are displayed, but results with windows of intermediate sizes lie in-between, as expected (data not shown).
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Our final experiment shows two neuronal processes (putative axons) which were not resolved in the original SLIM image (region marked as E in Fig. 6(a)).
Therefore, this paper describes the systematic development of a maintenance programme for the SLIM iMplementation Experience Region Noord- en Oost-Gelderland (SLIMMER), implemented in Dutch primary health care, using the Intervention Mapping (IM) protocol [ 23].
Compared to SLiMs in structured regions, SLiMs in disordered regions exhibit greater conservation than their flanking sequences.
Her prospects of claiming the presidency of the Paris region are slim.
The result keeps the Welsh region's slim hopes of progressing to the quarter-finals alive.
This greater relative conservation suggests that SLiMs in disordered regions are more likely to be biologically relevant binding sites than those sites within ordered regions.
They accuse him of tinkering rather than unleashing radical reforms to cut the regions' powers, slim the administration and squash separatist sentiment in Catalonia and the Basque country.
First, SLiMs in disordered regions are more accessible to domains since they are necessarily fully exposed.
Much like combinations of SLiMs in disordered regions that lead to combinatorial post-translational regulatory switches [ 55], enhancers integrate complex transcriptional circuitry to individual genes [ 97].
Study of manually extracted SH2 interaction sites in 11 most studied receptor tyrosine kinases provided experimental evidence that Tyr-SLiMs within disordered regions are more likely to be involved in interaction.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com