Sentence examples for slightly reducing levels from inspiring English sources

Furthermore, slightly reducing levels of PEX13, which assists in docking PEX5 at the membrane [ 35], ameliorates the physiological defects of pex4-1 [ 33].

We expect that a pex5 mutation that reduces PEX5 protein levels without otherwise impairing PEX5 function might ameliorate the peroxisomal defects of pex4-1, asuggesteded by the finding that slightly reducing levels of the PEX13 docking peroxin reduces the physiological defects of pex4-1 without notably impairing peroxisome function [ 33].

Whereas some mutations are associated with only slightly reduced levels or activity of VWF, others are associated with drastic reductions leading to severe disease.

The slightly reduced levels of G-GPx and E-GPx mRNA in Se-deficient human cell lines can only partially account for the decreased C-GPx activity in Se-deficient human cell lines.

Mutation of M504 to alanine, an amino acid, which is essential for ligand binding and which is situated in helix 5 of the ligand binding domain, abolishes hormone binding but still allows nuclear localization at only slightly reduced levels in the absence of hormone, whereas nuclear localization of EcRM504R is nearly abolished.

Chitin, which forms a cylindrical cable-like structure inside the lumen, is still found in the lumen in γCOP embryos, although at slightly reduced levels (Figure 6D, J).

Nevertheless, co-infected individuals presented significantly higher plasma concentrations of IL-10 and slightly reduced levels of TNF-α compared with HBV mono-infected patients (Figure 4).

Slightly reduced levels of Rev-erba were also observed, when rosiglitazone was omitted from the differentiation mix in 3T3-L1 cells but not in SGBS cells, again revealing an interspecies difference in the nuclear receptor regulation during adipogenesis.

As reported [3], thymocytes of p73−/− mice displayed only slightly reduced levels of apoptosis compared to WT controls, but it was lessened by the deletion of p53 (Fig. 4G).

This is the reason why mice heterozygous for the deletion of the β1 integrin gene have normal or only slightly reduced levels of αxβ1 integrins on their cells and are thus phenotypically normal.

We observed that strains lacking Lsm12 and Pbp4 were still able to form stress granules and P-bodies, although the stress granules formed at slightly reduced levels compared to wild-type (Figure 3).