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The detergent molecule is smaller than PIP2 and lacks the anionic headgroup, so it is not surprising that it binds to a slightly different site.
They report that different methodologies used to measure skinfold thicknesses increase variability (such as slightly different site locations, different types of callipers, use of right versus left side of the body, single versus multiple measurements, and different degrees of anthropometric training) but that skinfolds can be measured accurately and reliably by trained anthropometrists.
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The sensors were placed at ten appropriate, but slightly different sites on the upper part of the flexor muscles of the lower arm (Fig. 1 ), and ten measurements were done with each instrument before the next instrument was applied.
Both prophage-like elements were detected at the same genomic position and apparently integrated at slightly different sites into a coding region for a hypothetical protein (CULC22_01157 and CULC809_01141) that may represent the integration site of these phages in the C. ulcerans chromosome.
Finally, we recently showed that close homologues of PTPS-III with a slightly different active site motif named PTPS-VI were found in a few Sulfolobus species.
Interestingly, previous studies have suggested that mutations in the A2062 position of the 23S rRNA gene result in resistance to the 16-membered macrolides (e.g., josamycin), but not necessarily to the 15-membered macrolides (e.g., azithromycin), indicating a slightly different binding site [ 35- 37].
Based on Table 2, the associations between the common haplotypes of p53 gene and cancer risk were slightly different in different sites of oral cancer (oral cavity cancer vs hypopharyngeal/oropharyngeal cancer).
This great diversity probably provides the variability necessary for these FBG domains to form slightly different binding sites that could recognize different carbohydrates.
Interestingly, these three molecules are not exactly equal but exhibit small offsets in their density of states, which we attribute to slightly different adsorption sites and, therefore, slightly different local environments (the system contains a 2 × 2 supercell of the TCNE layer on top of a 3 × 3 NaCl supercell).
The use of non cognate amino acid by aaRS or truncated aaRS is well known [ 35] and the fact that YjeA active site is slightly different than the LysRS2 site may allow for the accommodation (R -β-lysine.
Figure 4A presents structures of Clade I introns (P. pusillum and B. melanospora) which have a U A pair followed by a bulged C. Clade II introns (P. polycephalum and B. utricularis) have a slightly different G-binding site of an A U pair followed by a bulged C. A third G-binding site variant was noted in the Clade III introns (P. compressum and P. didermoides; Figure 4C).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com