Sentence examples for slightly destabilizing from inspiring English sources

As previously noted the P19A mutation had the most profound destabilizing effect; the other mutations were only slightly destabilizing.

Free-energy analysis showed that D104N and A259T have a structural stabilizing effect, whereas S206T is slightly destabilizing (Table 3).

Thermodynamic and NMR based studies revealed that a Ψ residue can stabilize an RNA hairpin structure when located at a stem loop junction, and is slightly destabilizing when located in single-stranded loop regions [15].

Although the largest decreases in stability are associated with the three mutations on which we focus (L259S, R384G, and V280A), other slightly destabilizing mutations are also fixed during NP's evolution.

According to calculations, electron withdrawing substituents remarkably stabilize the HOMO and LUMO of AcTH, while electron donating ones slightly destabilize them.

Apart from Mg and stoichiometric MgH2, we find an additional, slightly destabilized phase, which is formed prior to MgH2 upon hydrogenation.

The insertion of ChBD in position 197, however, slightly destabilizes BlaP by 3.2 kJ·mol−1 (Table 1).

A moderate red-shift could thus reflect a slightly destabilized tertiary fold, without necessarily a loss of secondary structure.

When reduced with TCEP, the PhoQW104C-A128C PD was slightly destabilized relative to the wild type, with a T m app 52°C.

They observed that the insertion of this 72-residue folded domain at position 197 slightly destabilizes BlaP by 3.2 kJ·mol−1 (Table 1) [ 10].

As a result, the TIM barrel structure that houses the enzyme active site is slightly destabilized and the enzyme activity is reduced [ 10].