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Toward the end of the 1980s, however, increasing amounts of data showed the existence of slightly advantageous mutations and the effects of positive selection on them.
They showed that the effect of increasing pressure on UEL and LEL is negligible to slightly advantageous, while the effect of increasing temperature was disadvantageous.
Therefore, Ohta modified her original nearly neutral theory by incorporating the fate of slightly advantageous mutations, and proposed this modified theory as "nearly neutral theory of molecular evolution" in a series of two papers published in 1990 and1991.
Of course, if the fixation of slightly deleterious mutations is followed by that of slightly advantageous mutations, the function of the gene can be maintained in long-term evolution.
At that time, Ohta primarily focused on mutations that are "slightly deleterious" instead of both "slightly deleterious" and "slightly advantageous" mutations because of the wide belief of the "status quo" argument among molecular evolutionists.
Ohta incorporated this "status quo" argument to her nearly neutral theory in the early 1970s; therefore, Ohta did not see any need to discuss slightly advantageous mutations back then.
Similar(38)
The tax advantages of these plans are not expected to change, and even if marginal rates drop, making them slightly less advantageous, they are still attractive.
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"It is away from home, so it is slightly more advantageous for us than it is for them.
He's in a slightly more advantageous spot than Orbit Rain and Jimmy Chila, in that he at least has won one race, but that's it for this $350,000 purchase.
But by using activity monitors he shows that standing is only slightly more advantageous in terms of generating actual energy expenditure.
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CEO of Professional Science Editing for Scientists @ prosciediting.com