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It must be noted that following the transformation of raw spectral data to the corresponding first derivative, there is a slight shift of the vibrational mode location along the x-axis.
After crosslinking with glutaraldehyde, the amide I peak of the sericin hydrogel slightly shifted to 1655 cm−1 (Supplementary Fig. S2), suggesting that glutaraldehyde crosslinking leads to a slight transformation towards α-helix structure and does not cause significant structural transformations.
The atomic model of the near full-length S. solfataricus MCM (PDB entry 3F9V) was found to fit the entire Mcm4 electron density region, whereas slight rigid body transformations of the MCM AAA+ domain relative to the N-terminal region were allowed to best fit the electron density of Mcms 2, 3, 5, 6, and 7. A homology model based on the bacterial RecJ (PDB entry 1IR6) was used for docking of Cdc45.
MAK-4 did not have the same effect: on the contrary it showed a slight enhancement of cell transformation.
The ultrasonication longer than 10 min caused a slight decrease of the liposome diameter, indicating less transformation of the vesicle type with the ultrasonication time.
These structures have low transformation efficiency and slight risk of toxicity at high-dose applications which are considered as promising vectors for systemic administrations.
Therefore, if the amount of glucose in the medium of transformation experiment was increased, the slight amount of GA in production might be fully transformed to GB.
Between the speaking rate and the pitch-normalization, we have first normalized the speaking rate since the speaking rate transformation may result in slight modification of the pitch of the signals.
These variables were also processed after natural logarithm transformation, with only a slight reduction of their variability.
