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In p53+/−Mysm1−/− (p53het) mice, a slight but variable recovery of BM, thymic, and splenic cell numbers could be observed compared with Mysm1−/− mice (not shown).
There was also some slight, but variable, immunostaining with poly-AP antibody implying some antisense translation might also occur, though the relative paucity of immunostaining could reflect poor antigen avidity on the part of the antisense antibodies.
The finding of strong and consistent staining with poly-GA, poly-GP and poly-GR antibodies suggests that most of the aberrant translation relates to sense transcripts, though the slight, but variable immunostaining with poly-AP antibody implies some antisense translation might also occur.
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Notably, the increase of fluorescence intensity by CTLs established from 2 patients with unknown genetic mutations was also variable; a slight but significant change in UPN30 (MFI was 1.53), while completely undetectable even after alloantigen stimulation in UPN31 (MFI was 0.16).
Two additional DMG patients had two Ig transcripts using the same IGHV, IGHD and IGHJ genes but with slight differences in variable region or HCDR3 mutations.
Besides AGR2, CoCl2, as a hypoxia inducer, also showed slight and variable effects on cell proliferation (see in Fig. 1).
However, at these low transport rates, we cannot exclude that slight and variable osmotic imbalances marginally opened VRAC as steady-state efflux differed between experiments (compare Fig 8A E).
In this review, Colliver's re-analysis of the data showed that the extent of attitudinal changes to be slight and variable in direction.
Table 5 shows that the two treatment groups were well matched for all demographic variables except for a slight but statistically significant difference in age and the incidence of other types of preexisting lung disease with the patients without six month follow-up data being slightly older and having a greater incidence of preexisting lung disease of 'other' etiologies.
The within person variables, examining episodes of heightened depression and PTSD, showed a slight, but significant interaction effect on alcohol use.
After passive mobilization, there was a slight but significant increase in PPV (T0: 78.2 (70.9–81.9) %; T1: 80.0 (75.2–85.1) %, p < 0.029), without any change in other microcirculatory variables.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com