Therefore, it is necessary to discuss whether a slight change that would alter this methodological aspect interferes with the result of the examination, taking care to use manometric equipment and esophageal pH monitoring, as well as catheters with a recognized technical reliability.
It is recognized that crystallization is associated with molecular recognition events that lead to self-assembly, and that pharmaceutical function and thermodynamic stability can be altered with a slight change in the interacting molecules or their molecular network motifs.
The results also conveyed that the reaction temperature and reaction time were limiting conditions and a slight variation herein altered the biodiesel yield.
In conclusion, slight alterations in one player of Notch signaling alter the entire organism, emphasizing the fine-tuning character of this pathway in a high number of processes.
This last test tends to indicate that altered Nanobyk NPs induce a slight change in mitochondrial function.
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However, when the initial glycerol concentration of the culture was altered, only slight changes in the expression of CBY_9999 were observed.
Plausibly, a slight change in choice of molecules results in a significantly dissimilar analog of a drug while not altering its functioning on many targets.
For example, slight environmental changes alter our judgments and behavior without our realizing.
Using a modeled structure of the protein coded by the Sry1 locus (Sryα) interacting with DNA (cyan, Figure 5A), it can be seen that substitutions in amino acids 4, 21 and 76 (red, Figure 5A) may have a slight propensity to alter DNA binding stability and energy.
