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Although Ssk1 is the only known activator of Ssk2/ Ssk22, osmostress does cause slight activation of the Hog1 MAPK in ssk1 Δ sho1 Δ mutants, whereas no activation is observed in ssk2 Δ ssk22 Δ sho1 Δ mutants (Maeda et al. 1994; Reiser et al. 2000).
Furthermore, NOD2 binding to NLRP3 apparently is of transient nature as indicated by only slight activation of the reporter genes.
Interestingly, before inhibition occurred, we consistently saw a slight activation of zShal currents.
In addition, there is a slight activation of caspase 8 in these cells as well, which may amplify the apoptotic process.
The only evidence of the induction of the TGF-β signaling pathway in the resistant cells was upregulated TGF-β ligand expression and slight activation of SMAD2.
In the absence of H. pylori, TRAIL engagement only induced a slight activation of caspase-8 but not caspase-3 in AGS cells.
Similar(44)
As shown in Fig. 5, HGF did not increase overall MET phosphorylation levels, although, interestingly, a slight activation was seen in the minority of processed β-fragment of MET.
Activation of caspase 9 and 3 was attenuated when Annexin A2-WT was overexpressed, and only slight activation was detected with an over-expression of Annexin-K302A (Fig. 6B and 6C).
Slight activation was observed in the presence of Ca2+, Co2+, and Ba2+.
Slight activation may be due to contact activation during the preparation of the sample.
Slight activation is observed with RXRwt but only at the highest concentration of ligand.
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