Sentence examples for sliding clamp from inspiring English sources

A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.

Georgescu, R. E. et al. Structure of a sliding clamp on DNA.

It can capture the newly released A subunit, thus moving the sliding clamp up by ~2.5 base pairs.

Laurence, T. A. et al. Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy.

Kelch, B. A., Makino, D. L., O'Donnell, M. & Kuriyan, J. How a DNA polymerase clamp loader opens a sliding clamp.

(C) Six identical AAA+ modules attached to a sliding clamp on DNA will form a filament in the presence of ATP.

Snowden, T., Acharya, S., Butz, C., Berardini, M. & Fishel, R. hMSH4-hMSH5 recognizes Holliday junctions and forms a meiosis-specific sliding clamp that embraces homologous chromosomes.

Processive chromosomal replication requires ring-shaped sliding clamp factors that encircle DNA and anchor polymerases and other proteins of the replisome.

To extend our understanding of the structure/function relationship of the sliding clamp, we solved the crystal structure of the sliding clamp from Mycobacterium tuberculosis (M. tuberculosis), a human pathogen that causes most cases of tuberculosis (TB).

Thus, the sliding clamp seems to have evolved as an efficient mechanism for ensuring proficient DNA replication.

For processivity, PolIIIα binds to the DNA sliding clamp (β subunit) (Stukenberg et al., 1991).