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The axial slice location was similar between all the mice and was consistently located 1 mm in front of the posterior of the olfactory bulb (OB).
However, despite differences in visual appearance and small discrepancies between slice location, both acquired and simulated DTS showed similar structures and level of depth resolution.
T1 measurement was performed after ASL imaging by using the same imaging sequence at same slice location but with inversion recovery at different inversion times.
For each slice location, a rectangular region of interest (ROI) of 11×11 pixels was drawn into the brain parenchyma in the temporal lobe in the first image of every LD time series and was copied to all subsequent images of the same time series as well as to all corresponding images of the original ULD and the respective HYPR-LR post-processed time series.
An oncological radiologist inspected the images, and the slice location for BOLD imaging was chosen.
There were no apparent trends in wall thickness with slice location for either vein segment.
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f Slice locations of the DTS and CT slices.
The thick black line indicates the corresponding slice locations in b and c.
Moreover, we applied z-shim compensation to 5 of the 31 slice locations in the OFC region.
Structural imaging included a three-dimensional high-resolution T1-weighted volume (1 mm×1 mm×1 mm) and a two-dimensional high-resolution T1-weighted image set in the same slice locations as the functional scanning (0.94 mm×0.94 mm×5 mm).
Immediately following the functional imaging, high resolution anatomical spoiled gradient-recalled at steady state (SPGR) images (4 mm thick, no spacing, number of excitations = 2, TE = in phase, TR = 325 ms, FA = 90°, in plane resolution 256×256, bandwidth = 31.25) were collected at the same slice locations as the functional images.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com