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However, actigraphy still overestimates total sleep time compared to polysomnography, as it has a high sensitivity for detecting sleep, but is less reliable in detecting wakefulness (that is, reduced sleep specificity) [ 59].
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The accuracy, sensitivity (percentage correctly scored as sleep) and specificity (percentage correctly scored as awake) were calculated for actigraphy using high, medium, low and automatic threshold sensitivity settings of the actigraphy software.
The effects of immune factors such as endotoxin and cytokines on sleep reveal species specificity and usually strong dependence on parameters such as substance concentration, time relative to administration or infection with microbial products, and phase relation to sleep and/or the light-dark cycle.
60 It has been shown that actigraphy has a high sensitivity and specificity for detecting sleep start, sleep periods and awakenings.
When PCN is in the range of 2 6, the accuracy, sensitivity of NREM sleep and wake and specificity of all three stages reach to near-plateau, especially when PCN is greater than 4.
MEASUREMENTS AND RESULTS: ROC and cross-tabs analyses were used to evaluate the sensitivity and specificity of PSG-derived total sleep time, latency to persistent sleep, wake after sleep onset, and sleep efficiency for discriminating adults with primary insomnia from normal sleepers.
This type of assessment has been recommended to enhance screening efforts of primary care and other specialty area practitioners, as it is inexpensive, easily administered, and shows reasonable sensitivity and specificity in identifying sleep disruptions [ 35].
In relation to seizure control, the specificity of an abnormal sleep EEG and the positive predictive value of normal sleep EEG were 100%.
This paper discusses the methodology for selecting a set of relevant nonstationary features to increase the specificity of the obstructive sleep apnea detector.
Only in the case of headaches and sleep disorder, did sensitivity prevail over specificity (table 3 classification table).
As these latter cells have no direct immunological function, we use them as natural controls to test the specificity of any relationship between sleep and the immune system.
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