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Other outcome measures included sleep interference score on Daily Sleep Interference Scale (DSIS; 0 = pain did not interfere with sleep to 10 = pain completely interfered with sleep) and safety.
Sleep interference, on the other hand, was only seldomly mentioned and was not considered to be so serious.
Additionally, pregabalin was associated with decreased sleep interference and significant improvements in HRQoL measures.
Additionally, by week 1 and for the study's duration, 150 and 300 mg/day pregabalin significantly reduced weekly mean sleep interference scores.
Anxiety, depression, sleep interference, employment interference, relationship interference and decreased physical and social activity are important factors in overall morbidity and should be assessed and addressed.
15 Pregabalin improves QOL and lessens sleep interference.
The predetermined primary outcome measure was the Daily Pain and Sleep Interference Diary which quantified subjects' average 24 h pain and sleep interference.
This study assessed related sleep interference due to pain as a secondary outcome using a sleep interference diary similar to the other trials discussed.
Sleep interference scores were recorded in subjects' daily diaries upon awakening.
Baseline mean pain and sleep interference scores were comparable across treatment and age groups.
Physicians rated the severity of patients' pDPN (1 = mild, 2 = moderate, 3 = severe) and sleep interference.
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