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Pre-treatment MAP was similar for CRRT and SLED sessions (74.1 ± 10.0 vs 76.4 ± 13.1 mmHg, respectively, p = 0.34), but pressors were employed at the onset of therapy more frequently with CRRT (72% vs 49% for SLED, p < 0.01).
Similar(59)
Ciprofloxacin was cleared relatively rapidly with a half-life of 6.9 hours and a Ke of 0.108/hour during SLED compared with 11.9 hours and 0.057/hour post-SLED (P < 0.05).
There was no significant difference in SOFA score at RRT initiation between patients who received SLED or CRRT (p = 0.18).
On the other hand, pressors escalation was observed more often during CRRT sessions (39.5% vs 25.6% of SLED sessions, p = 0.13).
Pre- and post-treatment systolic and diastolic blood pressure values and vasopressors were not significantly different; however, post-treatment systolic blood pressure tended to be higher in the SLED cohort (P = 0.05) (Table 3).
Hemodynamic instability occurred during 22 (56.4%) SLED and 43 (50.0%) CRRT sessions (p = 0.51).
115 patients were treated with SLED-BD (total number of treatments n = 817) and 117 patients with CVVH (total number of treatments n = 877).The primary outcome measure, 90-day mortality, was similar between groups (SLED: 49.6% vs. CVVH: 55.6%, P = 0.43).
Kinematic peaks occurred earlier and were less variable for the sled acceleration compared to the acoustic stimulus (p < 0.03; Table 1).
Rosebud is a sled.
J. P. Stapp, an Air Force flight surgeon studying the "physiology of rapid deceleration," wanted to test his rocket sled on something resembling a human.
The sled slowed.
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