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These derivations can be skipped upon the first reading.
To test whether DNA methylation facilitates MeCP2 binding to exonic regions, we examined the changes in local MeCP2 occupancy caused by inhibition of DNA methylation using qPCR assays over the exons that were aberrantly skipped upon global DNA demethylation.
This section, including the full proof of the theorem, should be skipped upon first reading: The Results section includes a self-contained informal and graphical version of the proof to which the present section provides the formal background and further mathematical details.
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Intriguingly, exons with binding close to more of the four splice sites showed progressively stronger skipping tendency upon RBM10 OE (Fig 2E).
Upon graduating, she skipped college and landed a good job as an office administrator at S. G. Warburg & Company, a London investment bank.
Remarkably, the exon 6 skipped transcripts were still detectable upon a 1 10,000 dilution, thus suggesting that, if present, the levels of correct FVII transcripts associated to the mutation were below the 0.01% of the aberrant ones.
Building upon skipping drums and an slowly unfolding synth melody, Terry's latest flexes his prowess as an all-night club conductor.
Upon arriving at the conference, I nearly skipped the opening gala and fled to my room for a movie and room service, overwhelmed by the number of strangers.
Our previous study has shown that the reading frame can be corrected by an exon 50 skip upon transfection with h50AON1 [ 7].
And this in turn suggests one reason why Socrates might have skipped the question of why the psychologically just can be relied upon to do what is right.
Recent work by Alexakis and co-workers has demonstrated that skipped enynes can be prepared from enynyl chloride 293 and alkyl Grignard reagents upon exposure to Cu and L79.
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CEO of Professional Science Editing for Scientists @ prosciediting.com