Exact(2)
Minus-end-directed movement of lysosomes requires dynein (Harada et al., 1998), but we did not observe any lysosomal accumulation of dynein heavy chain in cells overexpressing Arl8b and SKIP (data not shown).
We did not observe KIF3B (kinesin-2) being recruited to lysosomes in cells overexpressing Arl8b and SKIP, and a motorless form of KIF1Bβ (kinesin-3) did not prevent the peripheral redistribution of lysosomes by overexpressed Arl8b and SKIP (data not shown).
Similar(58)
This early change in alternative splicing was not seen for LDLR exon 4 or 12 skipping, or for MVK exon 4 skipping (data not shown).
The maximum numbers for open categories were chosen according to the available M-SKIP data.
Twenty-two percent were lost to follow-up and 6%% of the patients skipped data collection at T1 (see Fig. 1).
Baseline characteristics of persons available for analyses versus those lost to follow-up or those who skipped data collection at T1 (N = 749).
Patients who skipped data collection were still willing to participate in future follow-up visits (e.g. at three years follow-up).
The percentage of older cancer and persons without cancer that were lost to follow-up or skipped data collection at one-year follow-up was comparable (p = 0.93).
Of the 503 participants, 116 (23%) were lost to follow-up and 29 (6%) patients skipped data collection at one-year follow-up (see Figure 1).
The proportion of OCP and YCP that were lost to follow-up or skipped data collection at T1 was comparable (p = 0.79).
The LNK exons are as conserved as constitutive exons and the conservation level of the ME exon is roughly equal to the individual cassette exons in exon skipping events with only one exon skipped (data not shown).
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