Patients present with erythema, skin nodules, dimpling of the skin (termed 'peau d'orange'), all features that develop rapidly, typically progressing within 6 months [ 1- 4].
Whereas B16 tumors grew rapidly in mice with substantial coat chimerism (termed fully chimeric mice herein), tumor growth in mice with overly white, FVB-derived skin (termed partial chimeras herein) was either marginal, yielding minute, largely necrotic tumors, or not observed at all.
To begin to assess whether mPGES-1 plays a role in fibrogenesis in SSc, we first examined whether mPGES-1 protein showed an altered expression pattern in dermal fibroblasts isolated from fibrotic lesions of early-onset diffuse SSc patients compared with those isolated from identical areas of healthy skin (termed normal fibroblast, or NF).
Health promotion is central to the management of psoriasis, a long-term inflammatory skin condition associated with a number of problematic health behaviours.
For experimentation, we loaded the Human Disease Ontology DOO) [ http://diseaseontology.sourceforge.net] (as of 15/12/2011) into OBO-Edit and selected three genetic skin diseases terms (cutis laxa, Hailey–Hailey disease and Rothmund Thomson syndrome) as seed terms for sibling generation.
In the 1981 interview in The Times, Dr. Burke described his process of creating artificial skin in terms that prefigured later advances in bioengineering like stem cell therapies.
I actually think we should be comfortable in our own skin in terms of the position that we're in, and not be afraid of the openness.
This study was undertaken to clarify the morphological features in the blood capillary and elastic fibre distribution of the human skin in terms of susceptibility to pressure sore development.
We observed no differences between mucosa and skin in terms of successful application of glue.
The divergence of the skin in terms of conserved connectivity depends partially on the inclusion of a group of genes of the keratin and MAGE family having a one-to-many and many-to-many homologous relationship.
