Previously we have shown that application of a cosmetic 'anti-ageing' product to photoaged skin under occlusion for 12 days can stimulate the deposition of fibrillin-1.
Secondly, it is known that the process of skin closure begins almost immediately upon MN removal, unless the skin area is kept under heavy occlusion.
The two-step preformulation strategy followed by three-level, three-variable, L9 (33) Taguchi robust orthogonal design employed was important in improving IDB NLCs key physicochemical aspects such as, entrapment efficiency, drug release (sustained), occlusion, skin deposition and physical stability.
But in a recent study [ 26], data was presented which shows that nitric oxide may not be the predominant factor in controlling skin circulation after occlusion.
Other less common complications include myocardial infarction, cardiovascular accidents, arterial occlusive lower limb ischemia, sinus vein thrombosis, mesenteric venous or arterial occlusion, and skin necrosis [ 28].
Sneddon's syndrome is a rare, progressive, non-inflammatory vasculopathy affecting the small- and medium-size arteries of the brain and skin, leading to their occlusion due to excessive endothelial proliferation.
Videomicroscopy was used to measure recruitment of skin capillaries after arterial occlusion.
Mutation in AGA causes a heritable lysosome storage disorder and is associated with changes in the facial skin, dental arches and occlusion [ 29, 30].
Impending tissue necrosis may occur as a result of inadvertent injection of filler into vessels supplying the mucosa or the skin, resulting in vessel occlusion.
Most cases of cutaneous candidosis occur in the skin folds or where occlusion by clothing or medical dressings produces abnormally moist conditions.
