The authors would like to express gratitude to Olgica Beslac, Dr Daniel Mettler, and Daniel Zalokar for their skillful assistance during the experiments, and to Jeannie Wurz for editing the manuscript.
The participants practice two to five times to become skillful before recording the experiment.
We wish to thank Antonella Asta and Filippo Pardossi for their skillful technical assistance during the experiments.
By skillful extensive genetic and biochemical experiments, the authors identified a new element that assists recognition of the proper start codon during the initiation step in the eukaryotic model system of yeast.
However, all these techniques are labor-intensive, time-consuming and requires skillful operator to perform the experiments, and thus limits their applications for large-scale studies [ 11], such as drug toxicity evaluation.
The authors are indebted to Christelle Barraclough (Genomics Platform) for assistance in microarray experiments and to Roswitha Rehm for skillful reading of the manuscript.
We thank professor H. K. Kimelberg (Albany Medical College, NY, USA) for providing facilities for a subset of the experiments, and C. J. Charniga for skillful technical assistance.
The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2407/11/300/prepub The authors thank Ms. M. Onitsuka for the skillful assistance in cell culture and co-culture experiments.
