Sentence examples for skewed usage from inspiring English sources

This should in turn be reflected in more codons and more amino acids showing skewed usage near boundaries.

Patients with a skewed usage of the TCRVβ in the peripheral blood were older than patients with a polyclonal T-cell repertoire (median age: 13 versus 10 years, P=0.013).

To determine which, and how many, codons and amino acids show significantly skewed usage in proximity to exon intron junctions, we considered the relative usage of all codons and amino acids as a function of distance from an exon intron junction, ignoring the codon in immediate proximity to the junction.

The slow evolution of essential genes in domains of high recombination is, however, explicable in terms of skewed nucleotide usage.

As a consequence of GC composition, protein-coding genes in lower GC genomes have skewed codon usage (Dufresne et al. 2005).

In these organisms, selective pressure to optimize translational efficiency during rapid growth can overcome drift and mutational bias, leading to highly skewed codon usage patterns within a genome.

The slow rate of evolution of essential genes in domains of high recombination, we conclude, is fully explained by their skewed nucleotide usage.

The third copy (FN0402) is only 177 bp long, is flanked by a long spacer and has a very skewed codon usage.

In the peripheral blood, 33 of 83 analyzed RCC patients (40%) showed a skewed TCRVβ usage, 23 (28%) of whom had a weakly skewed and 10 (12%) a strongly skewed repertoire (Table 2).

GC bias has been shown to carry over to amino acid composition of encoded proteins, producing amino acid bias (due to skewed codon usage, which was demonstrated for Prochlorococcus spp.; Dufresne et al. 2005).

However, it has been postulated that even when the effective number of codons alone suggests that P. falciparum is under stronger translational selection than P. vivax, most of the skewed codon usage can be attributed to compositional biases rather than stronger translational selection (Zilversmit et al. 2010).