Sentence examples for skewed expression from inspiring English sources

As the international wheat community continues to make rapid progress towards completion of an annotated reference wheat genome sequence [ 40, 78], we will in the future be able to assess the generality of the patterns we have observed here for all wheat genes, including those expressed at low levels and those with subtle or highly skewed expression of homoeoloci.

Overexpressed Notch1 and Hes1 were reported in skewed expression of CD4/CD8 T cells.

None of the 11 candidate genes with less than 100% peak overlap exhibited monoallelic or strongly skewed expression.

Skewed expression in favour of the maternal allele is due to a differentially methylated CpG-island within intron 2 of the RB1 gene.

To adjust for differences in library size and skewed expression of transcripts, we used the metric 'transcripts per million' (TPM) for each transcriptome [ 81].

To adjust for library sizes and skewed expression of transcripts, the estimated abundance values were normalized using the Trimmed Mean of M-values (TMM) normalization method included in the edgeR package [ 55].

Transcripts CNTNAP2-001, -002, and -003 did not show skewed allelic expression, which argues against CNTNAP2 imprinting, at least in adult human brain.

Genomic imprinting is an epigenetic phenomenon resulting in highly skewed (monoallelic) expression of genes in a parent-of-origin-specific manner.

This is in line with the activation-associated effector phenotype and the skewed TCR expression pattern found in T-LGL leukemia.

Such transient DMRs may be associated with parental-allele-specific or skewed allelic expression early in embryogenesis, but there is also evidence that they can give rise to stable imprinting of linked genes, although the DMRs themselves lose monoallelic methylation during embryogenesis (Duffié et al., 2014).

In the present case, development of normal male genitalia presumes a skewed inactivation, allowing expression of the SRY in the gonadal cell population [ 15].