Sentence examples for skeletal exposure from inspiring English sources

The approved 3 monthmonth iv dose provides the highest annual cumulative skeletal exposure of approved ibandronate regimens (12 mg) (Zaidi et al 2007), resulting in superior efficacy to daily oral ibandronate (Eisman et al 2008).

Pharmacodynamically, monthly oral ibandronate utilizes a non-linear dose increase versus the daily oral regimen (150 mg/month vs 2.5 mg/day), which more than doubles annual cumulative skeletal exposure (ACE; 10.8 mg with monthly vs 5.5 mg with daily oral treatment) (Zaidi et al 2007).

One study has suggested a role for transporter-mediated uptake, by OATP2B1, and efflux in skeletal muscle exposure to rosuvastatin.

Thus, we propose that epigenetic regulation of genes encoding myogenic and structural/contractile proteins may be part of an epigenetic memory that allows for a higher regenerative potential of skeletal muscle after exposure to lifelong physical activity.

As a consequence to hypobaric hypoxic exposure skeletal muscle atrophy is often reported.

PGC-1α accumulated in the nuclear fraction in mouse skeletal muscle following exposure to paraquat.

The incidence of antihistamine and skeletal muscle relaxant exposure in this study was similar to reports in the literature [ 1, 11, 19, 20].

In human skeletal muscle, insulin exposure led to an expected increase in phosphorylation of Akt, TBC1D1/D4 (detected using a PAS antibody) and GSK3, while exposure to the nitric oxide donor had no effect.

After 3 (series 2) and 6 (series 1) months of CS or air exposure, skeletal muscle (left EDL muscle and left soleus muscle) were quickly frozen in isopentane cooled with nitrogen.

A non-differential misclassification of antihistamine and skeletal muscle relaxant exposure produces a bias towards the null, potentially making our interpretation of increased risk of events more conservative [ 30].

The composite primary outcome of death, ED visit or hospitalization within 1-year of cohort entry occurred in 320,513 patients (17.7%).>> A total of 27,786 (1.5%) patients had a new skeletal muscle relaxant exposure in FY 2006.